In pathologic myopia, CNV may develop in what percentage of eyes with an axial length greater than 26.5 mm?

In pathologic myopia, the development of choroidal neovascularization (CNV) is closely associated with the elongation of the eyeball, particularly in individuals with an axial length exceeding 26.5 mm. Studies and clinical data indicate that the risk of CNV in these eyes can be significant due to the structural changes and retinal degeneration that accompany higher degrees of myopia.

Research indicates that approximately 5% to 10% of eyes with an axial length greater than 26.5 mm will develop CNV. This percentage reflects a recognized risk level that is often cited in the literature on pathologic myopia, making it a key figure for understanding the potential complications in patients with severe forms of nearsightedness. This risk stems from factors including thinning of the choroid, retinal stretching, and exposure of the retina to increased mechanical stress, which all contribute to vulnerability to CNV.

Thus, the range of 5% to 10% represents a critical point for practitioners assessing patients with pathologic myopia, as monitoring for CNV can be essential for timely intervention and prevention of vision loss.