Ocular histoplasmosis syndrome predominantly causes which type of inflammation that also damages the retina?

Ocular histoplasmosis syndrome primarily involves choroiditis, which is inflammation of the choroid, a layer of blood vessels and connective tissue located between the retina and the sclera. This condition is associated with the fungal infection caused by Histoplasma capsulatum, which often leads to the development of choroidal neovascularization (CNV).

As the choroid becomes inflamed, it can cause disruptions in the underlying retinal structure, leading to damage in the retinal pigment epithelium and photoreceptors. This inflammatory process can result in visual impairment, often due to the associated complications like macular scarring and hemorrhage.

In contrast, retinopathy refers to damage to the retina that can arise from various causes, but it is not the primary manifestation of ocular histoplasmosis. Uveitis involves inflammation of the uveal tract, including the iris, ciliary body, and choroid, but in the context of ocular histoplasmosis, choroiditis is more directly linked. Endophthalmitis is a severe inflammation of the entire eye, typically caused by an infection, which is not the primary feature of ocular histoplasmosis. Thus, the most relevant condition associated with ocular hist