What are the two most common causative associations with choroidal neovascularization (CNV)?

Prepare for the Posterior Segment Block 15 – AMD and Other Causes of CNV Test with detailed flashcards and multiple choice questions. Each question offers helpful hints and clear explanations to enhance your understanding. Ace your exam with confidence!

The most common causative associations with choroidal neovascularization (CNV) are age-related macular degeneration (AMD) and myopic degeneration. AMD is a leading cause of vision loss in the elderly, characterized by the growth of new blood vessels in the choroid that can invade the retina, leading to vision impairment. Myopic degeneration occurs in individuals with high myopia and can also lead to the development of CNV, particularly when there is stretching and thinning of the retinal structures.

In the context of the other options, while diabetic retinopathy is a significant cause of vision complications and can lead to neovascularization, it predominantly results in retinal neovascularization rather than choroidal neovascularization. Retinal vein occlusion and glaucoma also involve different mechanisms that do not primarily lead to CNV. Tractional detachment and RPE detachment refer to specific retinal pathologies that are not directly related to the common causes of CNV.

Thus, the link between AMD and myopic degeneration as the leading causes of CNV is well-established in ophthalmologic literature, making this pairing the correct answer.

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