What characterizes the AREDS early AMD grading stage?

The AREDS early AMD grading stage is characterized by the presence of multiple small drusen. Drusen are yellowish-white deposits under the retina, which are often indicative of age-related macular degeneration (AMD). In the early stage of AMD, multiple small drusen can be identified on examination, signifying the initial changes associated with the disease. These drusen can be a precursor to more advanced forms of AMD.

In contrast, having only large drusen would suggest a more advanced stage of the disease rather than early AMD. Significant retinal thinning typically occurs in later stages of AMD and is not a characteristic feature of early AMD. The absence of drusen entirely would not fit the definition of early AMD, as early changes are marked by the presence of small drusen. Thus, the presence of multiple small drusen is a key characteristic that helps in the classification and diagnosis of early AMD.