What fundus findings can accompany pseudoxanthoma elasticum (PXE) besides angioid streaks?

Pseudoxanthoma elasticum (PXE) is a genetic condition that affects the elastic tissue in the body, and it is associated with various ocular manifestations, particularly those affecting the fundus. Among the findings associated with PXE, angioid streaks are a classic feature; however, other changes can accompany this condition.

Optic nerve head drusen are associated with several systemic conditions, including PXE. They represent localized accumulations of abnormal tissue at the optic nerve head and can lead to complications such as visual field defects, which may occur in conjunction with mechanisms affected by the underlying connective tissue disarray seen in PXE.

In contrast, choroidal neovascularization, retinal detachments, and macular edema, while possible in PXE, do not have the same direct association. Choroidal neovascularization is more commonly linked with diseases that cause significant disruptions to the retinal pigment epithelium but is not a primary finding in PXE itself. This distinction is vital, as it demonstrates how PXE primarily leads to specific fundus changes related to elastic tissue degeneration and not necessarily the broader range of complications seen in other retinal diseases.

Thus, among the potential findings associated with PXE, optic nerve head drusen