What is a characteristic of Fibrovascular PED?

Fibrovascular Pigment Epithelial Detachment (PED) is prominently associated with wet Age-related Macular Degeneration (AMD), making it a key feature in the diagnosis and understanding of this condition. In wet AMD, there is a proliferation of new abnormal blood vessels (choroidal neovascularization, or CNV) which can lead to the formation of fibrovascular PEDs. These detachments represent a combination of elevated retinal pigment epithelium (RPE) layer and the presence of abnormal fibrovascular tissue underneath, contributing to vision loss.

This contrasts with characteristics attributed to dry AMD or drusen formations, which are not associated with the neovascular changes seen in wet AMD. The statement that it does not involve the RPE is incorrect as fibrovascular PEDs originate from alterations in the RPE layer itself. Thus, recognizing fibrovascular PED as a feature of wet AMD is essential for understanding the progression and potential treatments of this form of macular degeneration.