What neovascular AMD differential is uncommon, impacts older women, and usually manifests with peripheral retinal hemorrhage and exudation?

The condition described in the question is PEHCR (peripheral exudative hemorrhagic chorioretinopathy), which is indeed an uncommon differential diagnosis for neovascular age-related macular degeneration (AMD). This condition specifically impacts older women and is characterized by distinct clinical features, including peripheral retinal hemorrhage and exudation.

PEHCR often presents in elderly patients and is associated with changes in the retina that differ significantly from typical neovascular AMD findings. While macular degeneration itself is a more common cause of neovascular changes, PEHCR stands out because of its unique manifestations, particularly in the peripheral retina rather than centrally. The impact on older women aligns with demographic trends seen in this condition, further solidifying its relevance as an answer to the question.

In contrast, central serous chorioretinopathy typically affects a younger demographic and involves serous retinal detachment rather than the hemorrhagic exudation described. Choroidal melanoma, while it can cause similar symptoms, is a malignant tumor and not classified as a neovascular process commonly associated with AMD. Macular degeneration itself is a broader category that does not specifically match the uncommon nature or the detailed presentation (like peripheral hemorrhage) described in the question. Thus,