What variant of CNV type I is characterized by multiple, recurrent RPE detachments?

The correct answer highlights Polypoidal choroidal vasculopathy (PCV), which is a variant of CNV type I characterized by the presence of multiple, recurrent retinal pigment epithelium (RPE) detachments. In PCV, abnormal blood vessels grow and can lead to the development of polyp-like lesions beneath the RPE, resulting in fluid accumulation and subsequent detachments. This condition is particularly notable for its recurrent nature, which distinguishes it from other forms of CNV that may not exhibit the same pattern of detachment.

The classic presentations associated with other conditions, such as exudative age-related macular degeneration, may involve substantial neovascularization and associated damage, but these are often singular events or less recurrent compared to the behaviors observed in PCV. Additionally, while sero-sanguineous detachment might suggest fluid and blood accumulation, it does not specifically denote the recurrent and multi-locational aspects seen in PCV. Understanding these distinctions is crucial for effective diagnosis and treatment planning in the context of CNV pathology.