Which carotenoids are considered safe alternatives to beta-carotene as per AREDS2 findings?

Prepare for the Posterior Segment Block 15 – AMD and Other Causes of CNV Test with detailed flashcards and multiple choice questions. Each question offers helpful hints and clear explanations to enhance your understanding. Ace your exam with confidence!

Lutein and Zeaxanthin are considered safe alternatives to beta-carotene, particularly as indicated by the findings of the Age-Related Eye Disease Study 2 (AREDS2). These carotenoids are important because they are known to contribute to the health of the macula, the part of the retina responsible for central vision.

The AREDS2 study specifically focused on the impact of various supplements on the progression of age-related macular degeneration (AMD). Researchers found that lutein and zeaxanthin could potentially protect against visual loss associated with AMD. They work by filtering harmful blue light and providing antioxidant protection, which can help prevent damage to retinal cells.

In contrast, beta-carotene has been associated with potential risks, particularly in smokers, as it may increase the risk of lung cancer. This prompted researchers to seek safer alternatives, leading to the recommendation of lutein and zeaxanthin for those looking to support eye health without the risks associated with beta-carotene.

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