Which form of CNV is associated with a better prognosis when treated early?

Classic choroidal neovascularization (CNV) is characterized by well-defined, typically vascular networks that are associated with conditions like age-related macular degeneration (AMD). When treated early, classic CNV tends to have a better prognosis compared to other forms of CNV. This is primarily due to the clear and identifiable nature of the lesions, which allows for more effective treatment options such as anti-VEGF injections and photodynamic therapy.

In cases of classic CNV, early intervention can help to preserve central vision and reduce the risk of vision loss, as the more vascularized lesions are more responsive to treatment. The hallmark of classic CNV is that it generally appears more prominent on imaging studies, making it easier for clinicians to detect and initiate timely management.

Other forms of CNV, such as occult or submacular CNV, often present with less defined abnormal vascular patterns, which can complicate diagnosis and treatment. While these types may also benefit from early treatment, their inherently more challenging characteristics typically lead to less favorable outcomes compared to classic CNV.