Which patterns showed the lowest GA progression rates in dry AMD?

The lowest geographic atrophy (GA) progression rates in dry age-related macular degeneration (AMD) are typically observed in patterns categorized as "none" and "focal." This finding indicates that when GA is absent or restricted to small, focused areas, the disease exhibits a slower progression compared to other patterns.

The "none" pattern indicates that there is no observable GA, suggesting that the retina remains healthier in these cases, contributing to a slower disease course. The "focal" pattern, which is characterized by small, localized areas of GA, also limits the extent of vision loss, as only discrete regions of the retina are affected.

In contrast, other patterns such as "diffuse" and "geographic," or combinations of different patterns, show more extensive involvement of the retinal tissues, leading to faster progression of GA. These patterns contribute to a greater loss of retinal function and visual acuity, highlighting the impact of spatial distribution on disease severity and progression rates in dry AMD. Therefore, understanding these patterns aids in making clinical judgments and determining the prognosis for patients with AMD.