Which stage of AMD showed no discernible progression reduction when using supplements?

The stage of AMD that has shown no discernible progression reduction when using supplements is early or no AMD. This is important to note because studies indicate that while supplements may have a beneficial effect on reducing progression in more advanced stages of AMD, they do not demonstrate the same efficacy in the very early stages.

In this early stage, the disease process is just beginning, and the impact of nutritional supplements may not be sufficient to alter the natural course of the condition. This aligns with findings suggesting that interventions are more effective in moderate to advanced stages when there's already significant retinal damage and risk of vision loss. Understanding this distinction is crucial for clinicians in determining when to consider supplementation for patients at various stages of AMD.